Jacob House was founded in 2006 by Thakane Mitchell, RN, BSN, during her part-time work at Denver Health and at Brighton Gardens, where she served as a charge nurse in the skilled nursing unit. With a deep commitment to helping others, Thakane transitioned to full-time work at Jacob House in 2006, where she worked alongside her husband, Dr. David Mitchell, PhD, to provide essential services to individuals with intellectual disabilities and those in need.

Tragically, in 2011, Thakane was diagnosed with colon cancer. As her illness progressed, Dr. Mitchell demonstrated extraordinary dedication by resigning from his job to care for Thakane and their two young children. During this challenging time, he took on the management of Jacob House, which initially served only two clients. His personal sacrifices and unwavering commitment were instrumental to the organization's growth and continued success.

Thakane Mitchell, a crucial figure in the creation and mission of Jacob House, passed away on July 29, 2011. Her absence left a profound void, yet her legacy continues to inspire the staff and community to uphold her vision. The mission of Jacob House remains a testament to her dedication and enduring influence.

Today, Jacob House stands as a beacon of hope, offering a comprehensive range of services as a residential agency. It plays a vital role in supporting individuals with disabilities, advocating for their independence, and helping them develop essential lifelong skills. The services provided include a variety of residential supports such as host home services, family caregiver support, respite care, independent living services, community resources, advocacy, and transportation assistance. Jacob House strives to empower those it serves, enabling them to lead fulfilling lives with a robust network of support and care.